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4118 : Phase II study of autophagy inhibition with hydroxychloroquine (HCQ) and preoperative (preop) short course chemoradiation (SCRT) followed by early surgery for resectable ductal adenocarcinoma of the head of pancreas (PDAC).

Researchers

Presenter

  • Theodore S. Hong

Principal Investigators

  • Wenqing Jiang

  • Beow Y. Yeap

  • Jeffrey W. Clark

  • David P. Ryan

  • Lawrence Scott Blaszkowsky

  • Lorraine C. Drapek

  • Harvey J. Mamon

  • Janet E. Murphy

  • Jason Edward Faris

  • Eunice Lee Kwak

  • Jill N. Allen

  • Andrew X. Zhu

  • Lipika Goyal

  • Keith D Lillemoe

  • Cristina Ferrone

  • Thomas F. DeLaney

  • Carlos Fernandez-del Castillo

  • Alec Kimmelman

Medical Centers

  • NSABP/NRG Oncology, and The Massachusetts General Hospital, Boston, MA

  • Massachusetts General Hospital, Boston, MA

  • Massachusetts General Hospital Cancer Center, Boston, MA

  • Cancer Center at the Massachusetts General Hospital, Boston, MA

  • Dana-Farber Cancer Institute, Boston, MA

  • Massachusetts General Hosp Harvard Medcl School, Boston, MA

  • MGH Cancer Center, Brookline, MA

  • Department of Pathology, Massachusetts General Hospital, Boston, MA

  • New York University, New York, NY

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • N/A

Biomarkers

  • N/A

Drug/Treatment

  • Hydroxychloroquine

  • Gemcitabine

Outcome

  • N/A

Study Design

  • N/A

Phase

  • II

Study Id's

  • NCT01494155

Sponsors

  • N/A

Result

  • Final

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