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11537 : Association of circulating tumor DNA (ctDNA) tumor mutational burden (TMB) with DNA repair mutations and response to anti-PD-1/PD-L1 therapy in non-small cell lung cancer (NSCLC).

Researchers

Presenter

  • Andrew A. Davis

Principal Investigators

  • Young Kwang Chae

  • Sarita Agte

  • Alan Pan

  • Wade Thomas Iams

  • Marcelo Rocha De Sousa Cruz

  • Nisha Anjali Mohindra

  • Victoria Meucci Villaflor

  • Francis J. Giles

Medical Centers

  • Northwestern University, Chicago, IL

  • Northwestern Medicine Developmental Therapeutics Institute, Chicago, IL

  • Northwestern Memorial Hospital, Chicago, IL

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • N/A

Biomarkers

  • Programmed death-ligand 1

  • Circulating DNA

  • Tumor mutational burden

Drug/Treatment

  • N/A

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final