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TPS4597 : PROSPER: A phase III randomized study comparing perioperative nivolumab (nivo) vs. observation in patients with localized renal cell carcinoma (RCC) undergoing nephrectomy (ECOG-ACRIN 8143).

Researchers

Presenter

  • Lauren Christine Harshman

Principal Investigators

  • Naomi B. Haas

  • Charles G. Drake

  • David F. McDermott

  • Sabina Signoretti

  • David Cella

  • Rajan T Gupta

  • Lynne I. Wagner

  • Brian M. Shuch

  • Primo Lara

  • Toni K. Choueiri

  • Anil Kapoor

  • Daniel Yick Chin Heng

  • M. Dror Michaelson

  • Michael A.S. Jewett

  • Eliezer Mendel Van Allen

  • Daniel J. George

  • Michael Anthony Carducci

  • Mohamad Allaf

Medical Centers

  • Dana-Farber Cancer Institute, Boston, MA

  • Penn Medicine Abramson Cancer Center, Philadelphia, PA

  • Columbia University Medical Center and Herbert Irving Comprehensive Cancer Center, New York, NY

  • Beth Israel Deaconess Medical Center, Boston, MA

  • Brigham and Women's Hospital, Brookline, MA

  • Northwestern University, Feinberg School of Medicine, Chicago, IL

  • Duke University Medical Center, Durham, NC

  • Yale University School of Medicine, New Haven, CT

  • University of California, San Francisco, CA

  • Juravinski Cancer Centre and McMaster University, Hamilton, ON, Canada

  • Tom Baker Cancer Center - University of Calgary, Calgary, AB, Canada

  • Massachusetts General Hospital, Boston, MA

  • Princess Margaret Cancer Centre University Health Network, Toronto, Ontario, Canada

  • Duke University, Durham, NC

  • Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD

  • Johns Hopkins University School of Medicine, Baltimore, MD

Locations

  • United States

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • N/A

Biomarkers

  • X-Ray Repair Cross Complementing 1

Drug/Treatment

  • Nivolumab

Outcome

  • N/A

Study Design

  • Randomized

Phase

  • III

Study Id's

  • NCT02595918

  • NCT03055013

Sponsors

  • N/A

Result

  • N/A

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