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11589 : Genetic variants of Pin1 to predict benefit from irinotecan and oxaliplatin based treatment in patients with metastatic colorectal cancer (mCRC).

Researchers

Presenter

  • Mitsukuni Suenaga

Principal Investigators

  • Shu Cao

  • Wu Zhang

  • Dongyun Yang

  • Martin D. Berger

  • Jordan David West

  • Chiara Cremolini

  • Sara Lonardi

  • Francesca Battaglin

  • Yan Ning

  • Yuki Horiike

  • Noriko Yamamoto

  • Satoshi Okazaki

  • Yuji Miyamoto

  • Diana L. Hanna

  • Afsaneh Barzi

  • Fotios Loupakis

  • Alfredo Falcone

  • Heinz-Josef Lenz

Medical Centers

  • Division of Medical Oncology, USC Norris Comprehensive Cancer Center, Los Angeles, CA

  • Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Los Angeles, CA

  • USC Norris Comprehensive Cancer Center, Los Angeles, CA

  • Azienda Ospedaliero-Universitaria Pisana, Istituto Toscano Tumori, Pisa, Italy

  • Istituto Oncologico Veneto IOV - IRCCS, Padova, Italy

  • Dipartimento di Oncologia Clinica e Sperimentale, UOC Oncologia Medica I, Istituto Oncologico Veneto-IRCCS, Padova, Italy

  • University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA

  • Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan

  • Division of Pathology, Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan

  • University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA

  • Istituto Toscano Tumori, Pisa, Italy

  • Azienda Ospedaliero Universitaria Pisana, Pisa, Italy

  • University of Southern California, Los Angeles, CA

Locations

  • United States

  • Japan

  • Italy

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Gastroenterology (GU)

Disease

  • Colorectal Cancer

Biomarkers

  • p53

  • Casein Kinase 2 Alpha 1

  • Topoisomerase-1

Drug/Treatment

  • Oxaliplatin

  • Irinotecan

  • FOLFIRI

  • Oxaliplatin, 5-fluorouracil and folic acid

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final

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